Dr. Yao Wang, Curriculum Vitae
| Foreign language | |
| Mandarin Chinese (native, fluent) | |
| Employment | |
| 2021—current | Ophthalmic plastic and reconstructive surgeon, Eyesthetica, Los Angeles, CA |
| Education | |
| 2010 – 2014 | Doctor of Medicine, University of Michigan Medical School |
| 2006 – 2009 | BS in Biochemistry, University of Minnesota BA in Physiology, University of Minnesota |
| Post Graduate Education and Training | |
| July 2019 – June 2021 | ASOPRS Ophthalmic Plastic and Reconstructive Fellowship, Cedars-Sinai Medical Center |
| July 2018 – June 2019 | Neuro-Ophthalmology Fellowship, University of Minnesota |
| 2015 – 2018 | Ophthalmology Residency, University of Minnesota |
| 2014 – 2015 | Preliminary Medicine Internship, UCLA-OliveView |
| Medical Licensures | |
| active, 2019 – current | California Medical License |
| inactive, 2015 –2019 | Minnesota Medical License |
| Certifications | |
| October, 2019 | American Board of Ophthalmology |
| 2022 | American Society of Ophthalmic Plastic and Reconstructive Surgery |
| Professional Society Memberships | |
| 2015 –present | American Society of Ophthalmic Plastic and Reconstructive Surgery |
| 2016 – present | Women in Ophthalmology |
| 2015 – present | American Academy of Ophthalmology, member |
| 2015 – 2019 | Minnesota Academy of Ophthalmology, member |
| 2011 – 2012, 2016 – present | Association for Research in Vision and Ophthalmology, member |
| 2010 – 2014 | American Medical Association, member |
| Honors and Awards | |
| 05/2018 | Poland-Finke Chair Resident Award, University of Minnesota Named recognition for the third-year resident who excels clinically and academically during residency |
| 06/2017 | Harry Friedman Research Award, University of Minnesota Most outstanding resident research project of the year |
| 06/2016 | Oculoplastics Surgeon Award, University of Minnesota Most outstanding resident surgeon of the year |
| 05/2014 | Ophthalmology Scholarship Award for academic excellence, , University of Michigan |
| 11/2011 | Award of Excellence, Summer Biomedical Research Program, University of Michigan |
| 05/2009 | Summa Cum Laude with Highest Distinction, University of Minnesota |
| 05/2009 | Undergraduate Honors Thesis, University of Minnesota |
| 2006-2009 | Presidential Scholarship Award for academic excellence, University of Minnesota |
| Administrative Service | |
| 2015 – 2018 | Ophthalmology Residency Admissions Committee, University of Minnesota |
| Local, National, and International Service | |
| 2019 – 2021 | Fellow physician, LA Face, Shanghai, China |
| 2015 – 2018 | Phillips Neighborhood Clinic, volunteer, Minneapolis |
| 04/2017 | Mid-Year Forum, Advocacy Ambassador, Washington D.C |
| 2010 – 2014 | United Asian American Medical Student Association, Representative, Ann Arbor |
| 2008 – 2009 | Fairview Hospice, volunteer, Minneapolis |
| Employment | |
| 2009 – 2010 | ARCH Language Services, Mandarin Chinese Medical Interpreter |
| 2009 – 2010 | Retail Manager |
| 2019 – 2021 | MACRO Trials, clinical investigator |
| Grant Support | |
| 2016 – 2017 | Vitreoretinal Surgery Foundation Research Award |
| 2015 – 2016 | Vitreoretinal Surgery Foundation Research Award |
| 2011 | Summer Biomedical Research Award – NIH sponsored |
| Research activities | |
| 2019 – 2021 | Co-investigator for Tepezza (teprotumumab) for thyroid eye disease |
| 2019 – 2021 | Co-investigator for Immunovant for thyroid eye disease |
| 2018 – 2019 | Inter-observer Variability of Vertical Strabismus Measurements Using Alternative Prism Cover Testing and Single Maddox Rod |
| 2017– 2018 | Prevalence of Spontaneous Retinal Venous Pulsation in the Normal Population Using Fundus Real Time Imaging |
| 2016 – 2017 | Comparing the Outcomes of Vitrectomy, Scleral Buckle, Vitrectomy and Scleral Buckle, and Microincision Vitrectomy Surgery in Patients with Retinal Detachment |
| 2016 – 2017 | Thyroid Eye Disease Presenting with Superior Rectus/Levator Complex Involvement |
| 2016 – 2017 | Setting the Record Straight: Exodeviations are an Underappreciated Form of Strabismus in Thyroid Eye Disease |
| 2016 – 2017 | Quantitative Fundus Autofluorescence in Smokers Compared to Nonsmokers |
| 2016 –2017 | Choroidal Thickness in Smokers Compared to Non-smokers by Enhanced Depth Imaging Optical Coherence Tomography |
| 2014 | Changes in Skin Vascularity in a Murine Model for Postmastectomy Radiation |
| 2012 | Effect of Pigment Epithelium-Derived Factor on Hydrogen Peroxide-Exposed Human Retinal Pigment Epithelial Cells |
| 2008 – 2009 | Identifying Sites of Ubiquitination in Saccharomyces cerevisiae Mcm10 |
| 2007 – 2009 | Efficacy of Sedation Techniques and Economic Hardship Analysis |
| 2006 – 2007 | Understanding the Role of Human MCM10 in DNA Replication |
| Presentations | |
| Tarsal Inflammatory/Ischemic Syndrome (TIIS) as a Complication of Aesthetic Eyelid Surgery 2022 ASOPRS Meeting (poster), Chicago | |
| Indications and Complications of Periocular Dermal Fillers 2022 Multispecialty Aesthetic Conference (podium), San Diego | |
| Active and Inactive Thyroid Eye Disease: Symptom and Quality of Life Comparison in US patients 2021 AACE Annual Meeting (podium), virtual meeting | |
| Teprotumumab for the Treatment of Thyroid Eye Disease: Clinical Experience from Expanded Access Program (EAP) 2021 ARVO Annual Meeting (poster), virtual meeting | |
| Secondary Periorbital Hollows: Clinical Differentiation from Primary Age-Related Lower Eyelid/Cheek Interface Depressions 2022 Multispecialty Aesthetic Conference (podium), San Diego 2020 ASOPRS Annual Meeting (podium), virtual meeting | |
| Physician Perceptions of Active Thyroid Eye Disease in the United States 2019 AAO Annual Meeting (podium), San Francisco 2019 ASOPRS Annual Meeting (poster), San Francisco | |
| Impact of Thyroid Eye Disease on Patient Quality of Life as Perceived by US Ophthalmologists 2019 ASOPRS Annual Meeting (poster), San Francisco | |
| Inter-observer Variability of Vertical Strabismus Measurements Using Alternative Prism Cover Testing and Single Maddox Rod 2019 NANOS Annual Meeting (poster), Las Vegas | |
| Bilateral Optic Neuropathy Due to Spontaneous Globe Subluxations 2019 Wirtschafter Visiting Professor Lectureship (podium), Minneapolis | |
| Optic Nerve Sheath Fenestration for Treatment of Retrolaminar Silicone Oil Migration 2018 ASOPRS Annual Fall Meeting (podium), Chicago | |
| Comparing the Outcomes for Repair of Rhegmatogenous Retinal Detachment in Patients with and without Posterior Vitreous Detachment 2017 ARVO Annual International Conference (poster), Honolulu | |
| Thyroid Eye Disease Presenting with Superior Rectus/Levator Complex Involvement 2017 ASOPRS Annual Fall Meeting (podium), New Orleans | |
| Setting the Record Straight: Exodeviations are an Underappreciated Form of Strabismus in Thyroid Eye Disease 2017 ASOPRS Annual Fall Meeting (poster), New Orleans | |
| Contralateral Vision Loss – A Complication of Intraocular Silicone Oil Placement 2017 Wirtschafter Visiting Professor Lectureship (podium), Minneapolis | |
| Quantitative Fundus Autofluorescence in Smokers Compared to Non-smokers 2017 Annual Minnesota Lions Thanksgiving Event (podium), Minneapolis 2017 Dept. of Ophthalmology Annual Research Day (podium), Minneapolis 2017 ARVO Annual International Conference (poster), Baltimore 2017 Dept. of Ophthalmology Spring Research Symposium (poster), Minneapolis | |
| Intraocular Lens Dislocation in Pseudoexfoliation 2017 Harris Visiting Professor Lectureship (podium), Minneapolis | |
| A Case of Recurrent Primary CNS Lymphoma 2016 Knobloch Visiting Professor Lectureship (podium), Minneapolis | |
| Metastatic Breast Carcinoma to the Superior Oblique – in a Male 2016 ASOPRS Annual Fall Meeting (podium), Chicago 2016 Minnesota Academy of Ophthalmology Research Day (poster), St. Paul | |
| Horner’s Syndrome Following Intra-arterial Chemotherapy for Treatment of Retinoblastoma 2016 Letson Visiting Professor Lectureship (podium), Minneapolis | |
| Retinal Dystrophy – Case Presentations 2015 & 2016 Moorfields Eye Hospital (case presentations for Erik van Kujik, MD PhD) | |
| Effect of Pigment Epithelium-Derived Factor on Hydrogen Peroxide-Exposed Human Retinal Pigment Epithelial Cells (poster) 2014 Kellogg Eye Center Annual Research Day, Ann Arbor 2013 ARVO Annual International Conference, Fort Lauderdale 2012 University of Michigan Summer Biomedical Research Program Symposium, Ann Arbor | |
| Identifying Sites of Ubiquitination in Saccharomyces cerevisiae Mcm10 (poster) 2009 University of Minnesota Undergraduate Research Symposium, Minneapolis | |
| Publications | |
| Peer-reviewed publications: | |
| 1 | Ugradar S, Wang Y, Mester T, Kahaly GJ, Douglas RS. Teprotumumab for thyroid eye disease: early response is not required for benefit. Eye (Lond). 2021. |
| 2 | Ugradar S, Shi L, Wang Y, Mester T, Yang H, Douglas R. Teprotumumab for non-inflammatory thyroid eye disease (TED): evidence for increased IGF-1R expression. Eye (Lond). 2021; 35(9): 2607-2612. |
| 3 | Ugradar S, Braun J, Wang Y, Zimmerman E, Douglas RS. Facial and Eyelid Changes in Thyroid Eye Disease Are Reversed by Teprotumumab. Plast Reconstr Surg Glob Open. 2021;9(9):e3809. |
| 4 | Ugradar, Wang Y, Douglas R. Teprotumumab for Pediatric Thyroid Eye Disease. Ophthalmology. Submitted. |
| 5 | Azhdam AM, Wang Y, Douglas RS, Chang EE, Wu AW. Angioleiomyoma of the nasolacrimal duct: case report and literature review. Orbit. 2021:1-3. |
| 6 | Sears C, Wang Y, Bailey L, Kossler A, Turbin R, Subramanian P, Douglas R, Cockerham K. Early Efficacy of Teprotumumab for Thyroid Eye Disease with Compressive Optic Neuropathy. American Journal of Ophthalmology Case reports. 2021(23). |
| 7 | Wang Y, Massry G, Holds J. Complications of Periocular Dermal Fillers. Holds and Massry’s Facial Plastic Surgery Clinics. Elsevier. 2021. |
| 8 | Wang Y, Holds J, Douglas R, Massry G. The Spectrum of Aesthetic Canthal Suspension. Holds and Massry’s Facial Plastic Surgery Clinics. Elsevier. 2021. |
| 9 | Landsberger H, Wang Y, Douglas R. The Prominent Eye. Holds and Massry’s Facial Plastic Surgery Clinics. Elsevier. 2021. |
| 10 | Douglas RS, Wang Y, Dailey RA, et al. Teprotumumab in Clinical Practice: Recommendations and Considerations from the OPTIC Trial Investigators. J Neuroophthalmol. 2021; Publish Ahead of Print. |
| 11 | Ugradar S, Wang Y, Mester T, Kahaly G, Douglas R. Improvement of Asymmetric Thyroid Eye Disease with Teprotumumab. British Journal of Ophthalmology. Accepted 2021. |
| 12 | Wang Y, Holds J, Massry, G (editors) for Facial Plastic Surgery Clinics. Upcoming in 2022. |
| 13 | Ugradar U, Shi L, Wang Y, Yang H, Mester T, Douglas R. Teprotumumab for Non- Inflammatory Thyroid Eye Disease (TED): Evidence for Increased IGF-1R expression. American Journal of Ophthalmology. Submitted 2020. |
| 14 | Wang Y, Patel A, Douglas R. Single-stage Aesthetic Facial Reconstruction for Thyroid Eye Disease. Journal of Aesthetic Surgery. Submitted 2020. |
| 15 | Patel A, Galleda N, Wang Y, Ugradar S, Kumar A, Douglas R. Teprotumumab Reduces Extraocular Muscle and Orbital Fat Volume as Assessed by 3D Analysis in Thyroid Eye Disease. Ophthalmology. Submitted 2020. |
| 16 | Wang Y, Douglas RS, Horizon et al. Trends in Treatment of Active, Moderate-to-Severe Thyroid Eye Disease in the United States. Journal of Endocrine Society. Submitted 2020. |
| 17 | Wang Y, Padnaick-Silver L, Francis-Sedlak M, Douglas R. Physician-Perceived Impact of Thyroid Eye Disease on Patient Quality of Life in the United States. Ophthalmology and Therapy. 2020. |
| 18 | Wang Y, Douglas RS, Patel A, Holds J, Massry GG. Dermal Onlay Grafts: A Rescue Procedure for Secondary Inferior Periorbital Hollows. Aesthet Surg J. 2020. |
| 19 | Dumitrascu OM, Volod O, Bose S, Wang Y, Biousse V, Lyden PD. Acute ophthalmic artery occlusion in a COVID-19 patient on apixaban. J Stroke Cerebrovasc Dis. 2020;29(8):104982. |
| 20 | Ugradar S, Wang Y, Mester T, Douglas R. Teprotumumab for Asymmetric Thyroid Eye Disease. Ophthalmology. 2020. |
| 21 | Patel A, Wang Y, Frisenda J, Azizzadeh A, Massry G. Management Strategies for Eyelid Rehabilitation in Post-Facial Paralysis with Synkinesis. Azizzadeh and Nduka’s Management of Post-Facial Paralysis Synkinesis. Elsevier. 2020. |
| 22 | Wang Y, Douglas R. Thyroid Eye Disease. Albert and Jakiobec’s Principles and Practice of Ophthalmology. 4th Edition. 2020. |
| 23 | Wang Y, Lee S, McClelland C, Lee M. Idiopathic Intracranial Hypertension in a Transgender Woman on Exogenous Estrogen: Case Report and Review of the Literature. Canadian Journal of Ophthalmology. 2019. |
| 24 | Wagley S, Wang Y, Chen J, Lee M, McClelland C. Myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis Presenting as Idiopathic Orbital Inflammatory Syndrome. Journal of Neuro-ophthalmology. 2019. |
| 25 | Lee S, Wang Y, Asplund L, McClelland C, Lee M. Monocular hemianopia secondary to stroke. American Journal of Ophthalmology Case Reports. 2020 (19). |
| 26 | Mammo D, Wang Y, Lee M and McClelland C. Spontaneous Globe Luxation Induced Optic Neuropathy. Journal of Neuro-Ophthalmology. 2019. |
| 27 | Wang Y, Patel A, Douglas R. Thyroid Eye Disease: How A Novel Therapy May Change the Treatment Paradigm. Therapeutics and Clinical Risk Management. 2019 (3): 1305-1318. |
| 28 | Patel A, Wang Y, Massry G. Aesthetic Abstracts and Citations. Ophthalmic Plast Reconstr Surg. 2019. |
| 29 | Patel A, Wang Y, Massry G. Management of Post Blepharoplasty Lower Eyelid Retraction. Revision Facial Plastic Surgery: Correcting Bad Results. 2019. |
| 30 | Wang Y, Harrison A, Massry G. Defining the Brow Fat Pad: The Brow Fat Pad Suspension Suture. Advances in Cosmetic Surgery. Volume 2. |
| 31 | Wang Y, Ryu CL, Mokhtarzadeh A, Lee M, Harrison A, McClelland C. Optic Nerve Sheath Fenestration for Treatment of Retrolaminar Silicone Oil Migration. Ophthalmic Plast Reconstr Surg. 2019;35(2):e31-e34. |
| 32 | Wang Y, Mettu P, Broadbent T, et al. Thyroid eye disease presenting with superior rectus/levator complex enlargement. Orbit. 2019:1-8. |
| 33 | Wang Y, Tran T, Firl K, et al. Quantitative fundus autofluorescence in smokers compared to non-smokers. Exp Eye Res. 2019;184:48-55. |
| 34 | Wang Y, Tooley AA, Mehta VJ, Garrity JA, Harrison AR, Mettu P. Thyroid Orbitopathy. Int Ophthalmol Clin. 2018;58(2):137-179. |
| 35 | White R, Wang Y, Tang P, Montezuma S. Knobloch Syndrome Associated with Polymicrogyria and Early Onset of Retinal Detachment: Two Case Reports. BMC Ophthalmology. 2017;17(1):214. |
| 36 | Wang Y, Maltry A, Mokhtarzadeh A. Pleomorphic Adenoma of an Accessory Lacrimal Gland Masquerading as a Chalazion. Ophthalmology. 2017 Jul;124(7):952. |
| 37 | Wang Y, McCulley TJ, Doyle JJ, Chang J, Lee MS, McClelland CM. Brown Syndrome Following Upper Eyelid Ptosis Repair. Neuro-Ophthalmology. June 2017:1-3. |
| 38 | Wang Y, Mettu P, Maltry A, Harrison A, Mokhtarzadeh A. Metastatic Breast Carcinoma to the Superior Oblique in a Male. Ophthalmol Ther. May 2017. |
| 39 | Rodriguez JJ, Kung T, Wang Y, Nelson NS, Polyatskaya Y, Deshpande SS, Zheutlin AR, Donneys A, Buchman SR, Momoh AO. Changes in Skin Vascularity in a Murine Model for Post-Mastectomy Radiation. Annals of Plastic Surgery. 2016;76(5):494-498. |
| 40 | Wang Y, Smith TJ. Current Concepts in the Molecular Pathogenesis of Thyroid-Associated Ophthalmopathy. Invest Ophthalmol Vis Sci. 2014; 55(3):1735-1748. |
| Abstracts and/or proceedings: | |
| 1 | Douglas R, Wang Y, Bruch J, Anzeljc A, et al. Teprotumumab use in a real-world setting: expanded access program findings. Invest Ophthalmol Vis Sci. 2021. |
| 2 | Wang Y, Mester T, Ugradar U, Douglas R. Teprotumumab for the Treatment of Thyroid Eye Disease: Clinical Experience from Expanded Access Program (EAP). Invest Ophthalmol Vis Sci. 2021. |
| 3 | Thompson P, Eldweik E, Wang Y, Shyne M, Kassem A, Chen J, Bhatti T, Lee M, McClelland C. Near Infrared Videography vs. Direct Ophthalmoscopy for the Detection of Spontaneous Venous Pulsations. North American Neuro-Ophthalmology Society. 2019. |
| 4 | Wang Y, Ryan C, Yasin O, Parke W, Ryan E. Comparing the Outcomes for Repair of Rhegmatogenous Retinal Detachment in Patients with and without Posterior Vitreous Detachment. Invest Ophthalmol Vis Sci. 2018. |
| 5 | Wang Y, Firl K, Tran T, van Kuijk E, Montezuma S. Quantitative Fundus Autofluorescence in Smokers Compared to Non-smokers. Invest Ophthalmol Vis Sci. 2017;58(8):4853. |
| 6 | Murray J, Wang Y, White R, Firl K, Tran T, Feng A, Montezuma S. Choroidal Thickness in Smokers Compared to Non-smokers by Enhanced Depth Imaging Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017;58(8):1874. |
| 7 | Wang Y, Kothary PC, Del Monte MA. Effect of Pigment Epithelium-Derived Factor on Hydrogen Peroxide-Exposed Human Retinal Pigment Epithelial Cells. Invest Ophthalmol Vis Sci. 2012;53:4274. |